#FIRST-IN-CLASS.

BRP (BRINP2-Related Peptide)

Dermaseptin S5 (DS5) — frog skin antimicrobial peptide, anti-Leishmania

Elamipretide — SS-31 (MTP-131/Bendavia), mitochondria-targeted cardiolipin tetrapeptide

Cagrilintide

Lanreotide

Bremelanotide

Abaloparatide

Pemvidutide

Cotadutide

Brenipatide (FE 202767) — V2R-selective vasopressin analog, antidiuretic for DI

Dermaseptin S5 (DS5) — frog skin antimicrobial peptide, anti-Leishmania

Nocistatin (NST) — anti-allodynic neuropeptide opposing nociceptin/N/OFQ

Tripeptide-29 (Gly-Pro-Hyp) — collagen triple helix repeat cosmetic peptide

Palmitoyl Dipeptide-6 (Diffuporine) — skin barrier PPARβ/δ activating cosmetic lipopeptide

Spexin (SPX/Neuropeptide Q) — GALR2/GALR3 agonist, anorexigenic neuropeptide

Ac-SDKP (N-acetyl-Ser-Asp-Lys-Pro) — ACE substrate, anti-fibrotic hematopoietic tetrapeptide

Adropin (ENHO peptide) — energy homeostasis, metabolic, cardiovascular protective hormone

PNC-27 — p53-MDM2 chimeric anti-cancer membrane pore peptide

GSB-106 — BDNF loop 2 mimetic TrkB-activating antidepressant peptide

GK-2 — NGF/TrkA mimetic neuroprotective dipeptide, Gudasheva series

Oligopeptide-68 — tyrosinase-inhibiting skin brightening cosmetic peptide

Pal-AHK (Palmitoyl-Ala-His-Lys) — collagen-stimulating copper tripeptide variant

Rigin (Palmitoyl Tetrapeptide-7, Pal-GQPR) — anti-inflammatory cosmetic IgG Fc-mimetic

Vialox (Pentapeptide-3V) — nAChR-antagonist cosmetic neuromuscular anti-wrinkle peptide

Adipotide — prohibitin-targeting pro-apoptotic adipose vasculature peptide, weight loss

PE-22-28 — TREK-1 channel blocker, rapid-onset antidepressant peptide

Prostamax — Khavinson prostate tissue bioregulatory peptide

Testagen (KDE) — Khavinson testicular bioregulatory peptide, male reproductive aging

Ovagen — Khavinson ovarian tissue bioregulatory peptide, female reproductive aging

Chonluten (EDL) — Khavinson lung bronchial tripeptide

Livagen (KEDA) — Khavinson liver hepatoprotective tetrapeptide

Vilon (Lys-Glu / KE) — Khavinson thymic immunomodulatory dipeptide

Cardiogen — Khavinson cardiac muscle bioregulatory tetrapeptide

Bronchogen — Khavinson lung bronchial epithelial bioregulatory peptide

Cartalax (AEDL) — Khavinson cartilage/connective tissue bioregulatory tetrapeptide

Pancragen (KEDP) — Khavinson pancreatic bioregulatory tetrapeptide

Vesugen (KED) — Khavinson vascular endothelium bioregulatory tripeptide

Cortagen (AEDP) — Khavinson brain cortex neuroprotective tetrapeptide

Pinealon (Glu-Asp-Arg / EAR) — Khavinson pineal neuroprotective tripeptide

BRP (Brain Regeneration Peptide) — BDNF-mimetic neuroprotective research peptide

P21 — CNTF-related neurogenic peptide, intranasal BDNF/neurogenesis enhancer

PF-08653944 — Pfizer GLP-1R/GCGR dual agonist for obesity

Eloralintide (ZP4207) — long-acting amylin analog for obesity, once-daily

Ribupatide — T-cell immunomodulatory peptide for type 1 diabetes

Thymagen (Glu-Trp dipeptide) — thymic immunomodulator dipeptide

PEPITEM — ApoA-I-derived T-cell migration inhibitor peptide

Thymulin (FTS) — thymic nonapeptide, T-cell maturation hormone, zinc-dependent

Orexin-A (Hypocretin-1) — hypothalamic wakefulness neuropeptide, OX1R/OX2R agonist

MGF (Mechano Growth Factor / IGF-1Ec) — exercise-induced IGF-1 splice variant

IGF-1 DES (des(1-3)-IGF-1) — IGFBP-resistant truncated IGF-1 variant