public beta · research use only

EVIDENCE. IN THE OPEN.

An open hub for AI-generated peptide candidates. Every sequence gets a card. Every card ships with a recipe. Every fork is traceable.

cards 1739
targets 64
authors 1
reproduced 223

PeptideModel is an open research database for AI-generated peptide candidates. Every entry follows a five-level evidence pipeline — designed, computed, reproduced, synthesized, and bioassayed — that distinguishes AI proposals from experimentally validated sequences. Each card records the full prediction recipe (model, version, hardware, seeds, command) for independent reproducibility. All data is CC-BY-SA 4.0 and accessible via a free public API at api.peptidemodel.com. The platform currently indexes 1739 sequences across 64 biological targets.

Semaglutide FLAGSHIP weight loss & type-2 diabetes BPC-157 FLAGSHIP gut healing & tissue repair DF-3 ADVANCED muscle growth GIP (1-30) FLAGSHIP insulin release, obesity treatment Melanotan I FLAGSHIP skin darkening & sun-pain protection Tirzepatide ADVANCED weight loss & type-2 diabetes Retatrutide FLAGSHIP weight loss & metabolism TB-500 FLAGSHIP tissue repair & angiogenesis Oxytocin ADVANCED labor & social bonding CJC-1295 FLAGSHIP growth hormone release Setmelanotide ADVANCED genetic obesity treatment Sermorelin ADVANCED stimulates growth hormone release Cagrilintide NEWS appetite suppression & weight loss LL-37 ADVANCED kills bacteria & pathogens Elamipretide NEWS stabilizes cellular energy production MOTS-c ADVANCED energy metabolism & longevity Semaglutide FLAGSHIP weight loss & type-2 diabetes BPC-157 FLAGSHIP gut healing & tissue repair DF-3 ADVANCED muscle growth GIP (1-30) FLAGSHIP insulin release, obesity treatment Melanotan I FLAGSHIP skin darkening & sun-pain protection Tirzepatide ADVANCED weight loss & type-2 diabetes Retatrutide FLAGSHIP weight loss & metabolism TB-500 FLAGSHIP tissue repair & angiogenesis Oxytocin ADVANCED labor & social bonding CJC-1295 FLAGSHIP growth hormone release Setmelanotide ADVANCED genetic obesity treatment Sermorelin ADVANCED stimulates growth hormone release Cagrilintide NEWS appetite suppression & weight loss LL-37 ADVANCED kills bacteria & pathogens Elamipretide NEWS stabilizes cellular energy production MOTS-c ADVANCED energy metabolism & longevity

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A stapled peptide switched on a tumor-suppressor and two cancer drivers fell
In colorectal cancer cells and mice, the stapled peptide i7-01s-20 reactivated Beclin1 and degraded both EGFR and beta-catenin at once, and the effect vanished when Beclin1 was silenced.
ANTICANCER
Genes tied to GLP-1 drugs point to less depression, not more
A drug-target Mendelian randomization study put major depression 18 percent lower and bipolar disorder 39 percent lower for genetically predicted GLP-1 receptor activation, cutting against two years of psychiatric-safety scares built on observational data.
GLP-1R
GLP-1 drugs lowered heart risk in dialysis patients trials skipped
A TriNetX analysis of 1,688 matched pairs found GLP-1 receptor agonists cut major heart events, death, and even sepsis in dialysis patients with type 2 diabetes, a group the big outcome trials left out.
GLP-1R

browse by target · 53 targets indexed

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The grid of family cards becomes a body-map on-ramp. Pick a system — by tab, by the figure, or by the index — and the panel resolves to that region's targets, ranked by activity, one click from the full list.

view anterior · male · icon-led systems · mapped rig

how it works · platform pipeline · all cards

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1designed
1,739100.0%
2computed
1,71298.4%
3reproduced
42224.3%
4synthesized
42124.2%
5bioassayed
25414.6%

Every card carries a five-level status. Anyone can design; computation and reproduction require a recipe and attached artifacts; synthesis requires an LC-MS spectrum; assay requires a protocol and raw data. The funnel is steep because the schema is strict — and that's the point.

recent activity · live feed across all targets

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