pep-05625 v1 CC-BY-SA-4.0
Beta-defensin 115 antimicrobial peptide
A small protein fragment that kills or slows the growth of harmful microbes; used only as a lab research tool.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
SYNTHESIZED — literature evidence
Literature-extracted sequence peptide — synthesized for bioassay as documented in linked reference(s)
Fork this card to add platform evidence →
BIOASSAYED — literature evidence
Activity measured in linked reference(s) — IC50/MIC/cytotoxicity data
Fork this card to add platform evidence →
prediction metrics
ipTM0.000
pTM0.341
avg pLDDT54.4
ranking score0.504
STRUCTURE · PEP-05625 × ANTIMICROBIAL
ranking0.504
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
151015202530354045505556
GWIRRCYYGTGRCR KSCKEIERKKEKCG EKHICCVPKEKDKL SHIHDQKETSELYI
in the news
Prions are known for misfolding. An AI found antibiotics inside them. ANTIMICROBIAL · via ANTIMICROBIAL
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.5036904215812683 | boltz-2 |
▸3-letter notation
Gly-Trp-Ile-Arg-Arg-Cys-Tyr-Tyr-Gly-Thr-Gly-Arg-Cys-Arg-Lys-Ser-Cys-Lys-Glu-Ile-Glu-Arg-Lys-Lys-Glu-Lys-Cys-Gly-Glu-Lys-His-Ile-Cys-Cys-Val-Pro-Lys-Glu-Lys-Asp-Lys-Leu-Ser-His-Ile-His-Asp-Gln-Lys-Glu-Thr-Ser-Glu-Leu-Tyr-Ile
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Beta-defensin 115 antimicrobial peptide (pep-05625, v1). PeptideModel. https://peptidemodel.com/card/pep-05625
@peptide{pep05625,
sequence = {GWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKDKLSHIHDQKETSELYI},
target = {antimicrobial},
author = {peptidemodel},
year = {2026},
status = {bioassayed}
} related peptides
references
discussion
sign in to comment