pep-05565 v1 CC-BY-SA-4.0
Nisin-Z natural germ-killing peptide
A short protein fragment that kills or slows the growth of harmful microbes; experimental, not yet an approved drug.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
The peptide was actually made in a lab.
A chemistry service or a researcher ordered the sequence, it was manufactured, and mass spectrometry confirmed the right molecule was produced.
The peptide was tested on its target in a lab.
A binding or activity measurement confirmed that it actually does what the computer predicted — or didn't.
prediction metrics
ipTM0.000
pTM0.442
avg pLDDT54.3
ranking score0.523
STRUCTURE · PEP-05565 × ANTIMICROBIAL
ranking0.523
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
151015202530354045505557
MSTKDFNLDLVSVSKKNSG ASPRITSVSLCTPGCKTGA VMGCNMKTATCNCSIHVSK
in the news
Prions are known for misfolding. An AI found antibiotics inside them. ANTIMICROBIAL · via ANTIMICROBIAL
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.5231967568397522 | boltz-2 |
▸3-letter notation
Met-Ser-Thr-Lys-Asp-Phe-Asn-Leu-Asp-Leu-Val-Ser-Val-Ser-Lys-Lys-Asn-Ser-Gly-Ala-Ser-Pro-Arg-Ile-Thr-Ser-Val-Ser-Leu-Cys-Thr-Pro-Gly-Cys-Lys-Thr-Gly-Ala-Val-Met-Gly-Cys-Asn-Met-Lys-Thr-Ala-Thr-Cys-Asn-Cys-Ser-Ile-His-Val-Ser-Lys
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Nisin-Z natural germ-killing peptide (pep-05565, v1). PeptideModel. https://peptidemodel.com/card/pep-05565
@peptide{pep05565,
sequence = {MSTKDFNLDLVSVSKKNSGASPRITSVSLCTPGCKTGAVMGCNMKTATCNCSIHVSK},
target = {antimicrobial},
author = {peptidemodel},
year = {2026},
status = {computed}
} related peptides
references
discussion
sign in to comment