Class B GPCR / secretin receptor family

GHRHR

Growth Hormone-Releasing Hormone Receptor · UniProt Q02643 · gene GHRHR

browse 3 cards → upload → try → + watch target

anchor card · canonical reference for this target

anchor

Tesamorelin: Egrifta belly-fat reducer for people on HIV therapy

YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL · 44 aa · @peptidemodel

bioassayed pep-04441 @peptidemodel refs: 1

all cards · 3 candidates against GHRHR

#	id	title	author	status	refs	metric	♥
1	pep-10826	CJC-1295: long-acting growth hormone releaser	pe@peptidemodel		2	—	0
2	pep-04441	Tesamorelin: Egrifta belly-fat reducer for people on HIV therapy	pe@peptidemodel		1	—	0
3	pep-04431	Sermorelin: growth hormone-releasing drug (Geref)	pe@peptidemodel		8	—	0

1–3 of 3

target literature · 10 curated papers

[1]

Jetté, L. et al. 2005 Endocrinology Human Growth Hormone-Releasing Factor (hGRF)1–29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long-Lasting GRF Analog

cited by
1
cards

[2]

Ionescu, M. et al. 2006 The Journal of Clinical Endocrinology & Metabolism Pulsatile Secretion of Growth Hormone (GH) Persists during Continuous Stimulation by CJC-1295, a Long-Acting GH-Releasing Hormone Analog

cited by
1
cards

[3]

Vaughan, J. et al. 1992 Neuroendocrinology Neuroendocrinology 1992;56:539-549

cited by
2
cards

[4]

Ling, N. et al. 1984 Synthesis and in vitro bioactivity of human growth hormone-releasing factor analogs

cited by
1
cards

[5]

Gelato, M.C. et al. 1985 The Journal of Clinical Endocrinology & Metabolism Effects of Intravenous, Subcutaneous, and Intranasal Administration of Growth Hormone (GH)-Releasing Hormone-40 on Serum GH Concentrations in Normal Men*

cited by
1
cards

[6]

Rahman OF et al. 2026 JAAOS: Global Research and Reviews Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

cited by
1
cards

[7]

Chang Y et al. 2021 Annals of Translational Medicine A potentially effective drug for patients with recurrent glioma: sermorelin

cited by
1
cards

[8]

Sinha DK et al. 2020 Translational Andrology and Urology Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males

cited by
1
cards

[9]

Walker RF 2006 Clinical Interventions in Aging Sermorelin: A better approach to management of adult-onset growth hormone insufficiency?

cited by
1
cards

[10]

Prakash A et al. 1999 BioDrugs Sermorelin

cited by
1
cards

recent news 1 article

Australia's regulator flagged five peptides. One is a Phase 3 obesity drug.

@pavel 4d ago

discussion · 0 threads

No discussion threads yet.