pep-05664 v1 CC-BY-SA-4.0
Tick defensin 2 antimicrobial peptide
A naturally occurring peptide that kills or stops the growth of bacteria; used only as a lab research tool.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
SYNTHESIZED — literature evidence
Literature-extracted sequence peptide — synthesized for bioassay as documented in linked reference(s)
Fork this card to add platform evidence →
BIOASSAYED — literature evidence
Activity measured in linked reference(s) — IC50/MIC/cytotoxicity data
Fork this card to add platform evidence →
prediction metrics
ipTM0.000
pTM0.632
avg pLDDT72.0
ranking score0.703
STRUCTURE · PEP-05664 × ANTIMICROBIAL
ranking0.703
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
1510152025303540455055
GGFGCPFNIDN QGNCHNHCQSI RGRKGGYCHGI FKQTCKCYKPM GYKTRPPFILG
in the news
Prions are known for misfolding. An AI found antibiotics inside them. ANTIMICROBIAL · via ANTIMICROBIAL
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.7025392055511475 | boltz-2 |
▸3-letter notation
Gly-Gly-Phe-Gly-Cys-Pro-Phe-Asn-Ile-Asp-Asn-Gln-Gly-Asn-Cys-His-Asn-His-Cys-Gln-Ser-Ile-Arg-Gly-Arg-Lys-Gly-Gly-Tyr-Cys-His-Gly-Ile-Phe-Lys-Gln-Thr-Cys-Lys-Cys-Tyr-Lys-Pro-Met-Gly-Tyr-Lys-Thr-Arg-Pro-Pro-Phe-Ile-Leu-Gly
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Tick defensin 2 antimicrobial peptide (pep-05664, v1). PeptideModel. https://peptidemodel.com/card/pep-05664
@peptide{pep05664,
sequence = {GGFGCPFNIDNQGNCHNHCQSIRGRKGGYCHGIFKQTCKCYKPMGYKTRPPFILG},
target = {antimicrobial},
author = {peptidemodel},
year = {2026},
status = {bioassayed}
} related peptides
references
discussion
sign in to comment