pep-05538 v1 CC-BY-SA-4.0
Enterocin-HF antimicrobial peptide
A natural peptide that kills or slows bacteria; used only as a lab research tool.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
SYNTHESIZED — literature evidence
Literature-extracted sequence peptide — synthesized for bioassay as documented in linked reference(s)
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BIOASSAYED — literature evidence
Activity measured in linked reference(s) — IC50/MIC/cytotoxicity data
Fork this card to add platform evidence →
prediction metrics
ipTM0.000
pTM0.343
avg pLDDT51.1
ranking score0.478
STRUCTURE · PEP-05538 × ANTIMICROBIAL
ranking0.478
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
151015202530354045505558
MKKLTAKEMSQVVGGKYYGN GVSCNKKGCSVDWGKAIGII GNNSAANLATGGAAGWKS
in the news
Prions are known for misfolding. An AI found antibiotics inside them. ANTIMICROBIAL · via ANTIMICROBIAL
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.4777243137359619 | boltz-2 |
▸3-letter notation
Met-Lys-Lys-Leu-Thr-Ala-Lys-Glu-Met-Ser-Gln-Val-Val-Gly-Gly-Lys-Tyr-Tyr-Gly-Asn-Gly-Val-Ser-Cys-Asn-Lys-Lys-Gly-Cys-Ser-Val-Asp-Trp-Gly-Lys-Ala-Ile-Gly-Ile-Ile-Gly-Asn-Asn-Ser-Ala-Ala-Asn-Leu-Ala-Thr-Gly-Gly-Ala-Ala-Gly-Trp-Lys-Ser
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Enterocin-HF antimicrobial peptide (pep-05538, v1). PeptideModel. https://peptidemodel.com/card/pep-05538
@peptide{pep05538,
sequence = {MKKLTAKEMSQVVGGKYYGNGVSCNKKGCSVDWGKAIGIIGNNSAANLATGGAAGWKS},
target = {antimicrobial},
author = {peptidemodel},
year = {2026},
status = {bioassayed}
} related peptides
references
discussion
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