pep-05388 v1 CC-BY-SA-4.0
GPR15LG antiviral peptide
A small protein fragment being studied as a virus fighter; not an approved drug.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
SYNTHESIZED — literature evidence
Literature-extracted sequence peptide — synthesized for bioassay as documented in linked reference(s)
Fork this card to add platform evidence →
BIOASSAYED — literature evidence
Activity measured in linked reference(s) — IC50/MIC/cytotoxicity data
Fork this card to add platform evidence →
prediction metrics
ipTM0.000
pTM0.257
avg pLDDT46.1
ranking score0.420
STRUCTURE · PEP-05388 × ANTIMICROBIAL
ranking0.420
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
151015202530354045505557
KRRPAKAWSGRRTRLCCHR VPSPNSTNLKGHHVRLCKP CKLEPEPRLWVVPGALPQV
in the news
A Lab-Built Peptide Kills Superbugs and Revives Defeated Antibiotics ANTIMICROBIAL · via ANTIMICROBIAL
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.4200630784034729 | boltz-2 |
▸3-letter notation
Lys-Arg-Arg-Pro-Ala-Lys-Ala-Trp-Ser-Gly-Arg-Arg-Thr-Arg-Leu-Cys-Cys-His-Arg-Val-Pro-Ser-Pro-Asn-Ser-Thr-Asn-Leu-Lys-Gly-His-His-Val-Arg-Leu-Cys-Lys-Pro-Cys-Lys-Leu-Glu-Pro-Glu-Pro-Arg-Leu-Trp-Val-Val-Pro-Gly-Ala-Leu-Pro-Gln-Val
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). GPR15LG antiviral peptide (pep-05388, v1). PeptideModel. https://peptidemodel.com/card/pep-05388
@peptide{pep05388,
sequence = {KRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV},
target = {antimicrobial},
author = {peptidemodel},
year = {2026},
status = {bioassayed}
} references
discussion
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