pep-05361 v1 CC-BY-SA-4.0
Defensin-like protein 1 cancer-fighting peptide
A short protein fragment studied in the lab for its ability to kill or slow cancer cells; experimental, not yet an approved drug.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
The peptide was actually made in a lab.
A chemistry service or a researcher ordered the sequence, it was manufactured, and mass spectrometry confirmed the right molecule was produced.
The peptide was tested on its target in a lab.
A binding or activity measurement confirmed that it actually does what the computer predicted — or didn't.
prediction metrics
ipTM0.000
pTM0.739
avg pLDDT78.4
ranking score0.775
STRUCTURE · PEP-05361 × ANTICANCER
ranking0.775
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
15101520253035404547
LLGRCKVKSNRFHGPC LTDTHCSTVCRGEGYK GGDCHGLRRRCMCLC
in the news
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.7750031352043152 | boltz-2 |
▸3-letter notation
Leu-Leu-Gly-Arg-Cys-Lys-Val-Lys-Ser-Asn-Arg-Phe-His-Gly-Pro-Cys-Leu-Thr-Asp-Thr-His-Cys-Ser-Thr-Val-Cys-Arg-Gly-Glu-Gly-Tyr-Lys-Gly-Gly-Asp-Cys-His-Gly-Leu-Arg-Arg-Arg-Cys-Met-Cys-Leu-Cys
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Defensin-like protein 1 cancer-fighting peptide (pep-05361, v1). PeptideModel. https://peptidemodel.com/card/pep-05361
@peptide{pep05361,
sequence = {LLGRCKVKSNRFHGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC},
target = {anticancer},
author = {peptidemodel},
year = {2026},
status = {computed}
} references
[1] source scaffold
discussion
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