pep-05283 v1 CC-BY-SA-4.0
Beta-defensin 105A anticancer peptide
A lab-studied peptide being explored for its ability to fight cancer cells; experimental, not an approved drug.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
The peptide was actually made in a lab.
A chemistry service or a researcher ordered the sequence, it was manufactured, and mass spectrometry confirmed the right molecule was produced.
The peptide was tested on its target in a lab.
A binding or activity measurement confirmed that it actually does what the computer predicted — or didn't.
prediction metrics
ipTM0.000
pTM0.643
avg pLDDT73.2
ranking score0.714
STRUCTURE · PEP-05283 × ANTICANCER
ranking0.714
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
1510152025303540455051
GLDFSQPFPSDEFAVCE SCKLGRGKCRKECLENE KPDGNCRLNFLCCRERI
in the news
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.7139951586723328 | boltz-2 |
▸3-letter notation
Gly-Leu-Asp-Phe-Ser-Gln-Pro-Phe-Pro-Ser-Asp-Glu-Phe-Ala-Val-Cys-Glu-Ser-Cys-Lys-Leu-Gly-Arg-Gly-Lys-Cys-Arg-Lys-Glu-Cys-Leu-Glu-Asn-Glu-Lys-Pro-Asp-Gly-Asn-Cys-Arg-Leu-Asn-Phe-Leu-Cys-Cys-Arg-Glu-Arg-Ile
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Beta-defensin 105A anticancer peptide (pep-05283, v1). PeptideModel. https://peptidemodel.com/card/pep-05283
@peptide{pep05283,
sequence = {GLDFSQPFPSDEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRERI},
target = {anticancer},
author = {peptidemodel},
year = {2026},
status = {computed}
} related peptides
references
discussion
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