pep-05267 v1 CC-BY-SA-4.0
Defensin alpha-4 anticancer peptide
A peptide studied in the lab for its ability to kill or slow the growth of cancer cells; experimental, not yet an approved drug.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
SYNTHESIZED — literature evidence
Literature-extracted sequence peptide — synthesized for bioassay as documented in linked reference(s)
Fork this card to add platform evidence →
BIOASSAYED — literature evidence
Activity measured in linked reference(s) — IC50/MIC/cytotoxicity data
Fork this card to add platform evidence →
prediction metrics
ipTM0.000
pTM0.486
avg pLDDT75.6
ranking score0.702
STRUCTURE · PEP-05267 × ANTICANCER
ranking0.702
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
1510152025303540455052
MRTLAILAAILLF ALLAQAKSLQETA DDAATQEQPGEDD QDLAVSFEENGLS
in the news
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.7020208239555359 | boltz-2 |
▸3-letter notation
Met-Arg-Thr-Leu-Ala-Ile-Leu-Ala-Ala-Ile-Leu-Leu-Phe-Ala-Leu-Leu-Ala-Gln-Ala-Lys-Ser-Leu-Gln-Glu-Thr-Ala-Asp-Asp-Ala-Ala-Thr-Gln-Glu-Gln-Pro-Gly-Glu-Asp-Asp-Gln-Asp-Leu-Ala-Val-Ser-Phe-Glu-Glu-Asn-Gly-Leu-Ser
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). Defensin alpha-4 anticancer peptide (pep-05267, v1). PeptideModel. https://peptidemodel.com/card/pep-05267
@peptide{pep05267,
sequence = {MRTLAILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDLAVSFEENGLS},
target = {anticancer},
author = {peptidemodel},
year = {2026},
status = {bioassayed}
} related peptides
references
discussion
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