pep-05253 v1 CC-BY-SA-4.0
RPS14 anticancer peptide
A short protein fragment studied in the lab for its potential to fight cancer cells; experimental, not yet an approved drug.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
SYNTHESIZED — literature evidence
Literature-extracted sequence peptide — synthesized for bioassay as documented in linked reference(s)
Fork this card to add platform evidence →
BIOASSAYED — literature evidence
Activity measured in linked reference(s) — IC50/MIC/cytotoxicity data
Fork this card to add platform evidence →
prediction metrics
ipTM0.000
pTM0.639
avg pLDDT75.2
ranking score0.729
STRUCTURE · PEP-05253 × ANTICANCER
ranking0.729
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
1510152025303540455053
MAKKPWKKKYGYGIRPCQ RCGHVGPGLIRKYGLNLC RQCFREIAHKLGFKKLD
in the news
details
▸full evidence table1 metrics
| metric | value | tool |
|---|---|---|
| ranking score | 0.7291716933250427 | boltz-2 |
▸3-letter notation
Met-Ala-Lys-Lys-Pro-Trp-Lys-Lys-Lys-Tyr-Gly-Tyr-Gly-Ile-Arg-Pro-Cys-Gln-Arg-Cys-Gly-His-Val-Gly-Pro-Gly-Leu-Ile-Arg-Lys-Tyr-Gly-Leu-Asn-Leu-Cys-Arg-Gln-Cys-Phe-Arg-Glu-Ile-Ala-His-Lys-Leu-Gly-Phe-Lys-Lys-Leu-Asp
▸recipeboltz-2 2.2.1
| parameter | value |
|---|---|
| model | boltz-2 2.2.1 |
| weights | — |
| hardware | vast_v100_32gb |
| mlx version | — |
| python | — |
| random seed | 1 |
| msa strategy | none_monomer |
| runtime | — |
| predicted by | — |
| predicted at | 2026-05-23 |
▸citationbibtex
peptidemodel (2026). RPS14 anticancer peptide (pep-05253, v1). PeptideModel. https://peptidemodel.com/card/pep-05253
@peptide{pep05253,
sequence = {MAKKPWKKKYGYGIRPCQRCGHVGPGLIRKYGLNLCRQCFREIAHKLGFKKLD},
target = {anticancer},
author = {peptidemodel},
year = {2026},
status = {bioassayed}
} related peptides
references
discussion
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