pep-05073 v1 CC-BY-SA-4.0
Er-22 pheromone blood-sugar peptide
An experimental peptide designed to act like the gut hormone that tells the body to lower blood sugar and curb hunger, not an approved medicine.
status
Someone proposed this peptide.
A researcher, an agent, or an algorithm wrote down the sequence and picked a target to hit.
A computer predicted how the peptide binds to its target.
An AI model like OpenFold3 or AlphaFold built a 3D structure and scored how well it fits the binding site.
Someone else ran the same prediction and got the same result.
A second contributor repeated the computation on their own hardware and the scores matched.
The peptide was actually made in a lab.
A chemistry service or a researcher ordered the sequence, it was manufactured, and mass spectrometry confirmed the right molecule was produced.
The peptide was tested on its target in a lab.
A binding or activity measurement confirmed that it actually does what the computer predicted — or didn't.
prediction metrics
ipTM0.731
pTM0.713
avg pLDDT43.2
ranking score0.805
STRUCTURE · PEP-05073 × GLP-1R
ranking0.805
target interface 4.5Å peptide drag rotate · ctrl+scroll zoom · right-click pan
sequence
1510152025303537
DICDIAIAQCSLTLCQDCE NTPICELAVKGSCPPPWS
in the news
details
▸full evidence table2 metrics
| metric | value | tool |
|---|---|---|
| ipTM | 0.7312084436416626 | openfold3-mlx |
| ranking score | 0.8045443296432495 | openfold3-mlx |
▸structural qualityopenfold3
| metric | value | note |
|---|---|---|
| gpde | 0.809 | global PDE — lower = better |
| disorder | 0.154 | fraction disordered |
| chain pair ipTM (A, B) | 0.731 | interface quality |
▸3-letter notation
Asp-Ile-Cys-Asp-Ile-Ala-Ile-Ala-Gln-Cys-Ser-Leu-Thr-Leu-Cys-Gln-Asp-Cys-Glu-Asn-Thr-Pro-Ile-Cys-Glu-Leu-Ala-Val-Lys-Gly-Ser-Cys-Pro-Pro-Pro-Trp-Ser
▸recipeopenfold3-mlx 0.3.1
| parameter | value |
|---|---|
| model | openfold3-mlx 0.3.1 |
| weights | — |
| hardware | — |
| mlx version | — |
| python | — |
| random seed | — |
| msa strategy | — |
| diffusion samples | 1 |
| runtime | 1771s |
| predicted by | mlx@peptide |
| predicted at | 2026-04-14 |
▸citationbibtex
peptidemodel (2026). Er-22 pheromone blood-sugar peptide (pep-05073, v1). PeptideModel. https://peptidemodel.com/card/pep-05073
@peptide{pep05073,
sequence = {DICDIAIAQCSLTLCQDCENTPICELAVKGSCPPPWS},
target = {glp-1r},
author = {peptidemodel},
year = {2026},
status = {computed}
} related peptides
references
discussion
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