Neuroprotective peptides modulate cognitive function, anxiety, and neuroplasticity. Semax (MEHFPGP) is an ACTH(4-7) analog with a PGP stabilizer tail, studied for cognitive enhancement and stroke recovery. Selank (TKPRPGP) is a tuftsin analog with anxiolytic properties. DSIP (delta sleep-inducing peptide) is a 9-residue peptide involved in sleep architecture regulation.
Most clinical evidence comes from Russian research programs. Western replication is limited but growing.
Groups peptides by what they do, not what they bind. There's no PDB or UniProt — the target is a function, not a molecule. For receptor-level structure, open a molecular target like GHSR.
TKPRPGP · 7 aa · @peptidemodel
| # | id | title | author | status | refs | ipSAE_d0chn | ♥ |
|---|---|---|---|---|---|---|---|
| 1 | pep-00006 | Selank: Russia-approved anxiety & mood peptide (TKPRPGP) | pe@peptidemodel | 22 | — | 0 | |
| 2 | pep-00005 | Semax: brain-protecting nootropic drug approved in Russia | pe@peptidemodel | 6 | — | 0 | |
| 3 | pep-10965 | Nocistatin: natural pain-modulating brain peptide | pe@peptidemodel | 21 | — | 0 | |
| 4 | pep-00007 | DSIP: natural brain peptide linked to sleep and stress control | pe@peptidemodel | 3 | — | 0 | |
| 5 | pep-10929 | P21: brain-boosting peptide derived from a nerve-growth protein (CNTF) | pe@peptidemodel | 5 | — | 0 | |
| 6 | pep-10933 | Brain-protective peptide (Cortagen / AEDP) | pe@peptidemodel | 1 | — | 0 | |
| 7 | pep-10932 | Pinealon: brain-protective peptide (Glu-Asp-Arg / EAR) | pe@peptidemodel | 1 | — | 0 | |
| 8 | pep-10931 | Brain Regeneration Peptide (BRP): experimental appetite-suppressing brain peptide | pe@peptidemodel | 1 | — | 0 |
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