rhodopsin-like GPCR (class A) · Homo sapiens

AVPR1B

V1b receptor
vasopressin V1b receptor · UniProt P47901
brain

Vasopressin V1b receptor. Expressed in anterior pituitary, mediates ACTH release. Gq-coupled.

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anchor card · canonical reference for this target

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Vasopressin — Diabetes insipidus, enuresis

CYFQNCPRG · 9 aa · @peptidemodel

bioassayed pep-04423 @peptidemodel refs: 3

all cards · 5 candidates against AVPR1B

# id sequence title author status refs metric
1 pep-10872 CYFQNCPRD Desmopressin dDAVP pe@peptidemodel
2 0
2 pep-10300 CIQNCPG AVPR2 ligand CHEMBL1817756 (7-mer) pe@peptidemodel
1 0
3 pep-10299 CFINNCPG AVPR2 ligand CHEMBL1817752 (8-mer) pe@peptidemodel
1 0
4 pep-10298 CFIQNCPG AVPR2 ligand CHEMBL1817703 (8-mer) pe@peptidemodel
1 0
1–5 of 5

lineage families · 1 families

follistatin-df 1 cards
pep-04423 CYFQNCPRG Vasopressin — Diabetes insipidus, enuresis

target literature · 6 curated papers

[1]
Han, JuliaJung, Jae HungBakker, Caitlin J.Ebell, Mark H.Dahm, Philipp 2018 BJU International Desmopressin for treating nocturia in men
cited by
1
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[2]
Desborough, M.J.R.Oakland, K.A.Landoni, G.Crivellari, M.Doree, C.Estcourt, L.J. 2017 Journal of Thrombosis and Haemostasis Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomized controlled trials
cited by
1
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[3]
Wiśniewski, K. et al. 2011 Journal of Medicinal Chemistry New, Potent, Selective, and Short-Acting Peptidic V1aReceptor Agonists
cited by
3
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[4]
Landry Donald W. et al. 2001 New England Journal of Medicine The Pathogenesis of Vasodilatory Shock
cited by
1
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[6]
Sands Jeff M. et al. 2009 Seminars in Nephrology The Physiology of Urinary Concentration: An Update
cited by
1
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