CATEGORY · MULTI-MECHANISM

Anti-Aging

longevity
anti-aging and longevity peptides
aging skin

Anti-aging peptides target cellular senescence, telomere maintenance, and immune reconstitution. Epithalon (AEDG), a Khavinson tetrapeptide, is reported to activate telomerase. Thymosin Alpha-1 is a 28-residue immunomodulator used clinically for hepatitis B and as an immune adjuvant.

The field is early-stage with limited Western clinical data for most candidates. Khavinson bioregulator peptides originate from Russian research programs with decades of preclinical work but few RCTs by Western standards.

browse 1 cards → upload → try → + watch target
What is a category target?

Groups peptides by what they do, not what they bind. There's no PDB or UniProt — the target is a function, not a molecule. For receptor-level structure, open a molecular target like GHSR.

anchor card · canonical reference for this target

anchor

Epithalon: experimental longevity peptide (Epitalon / AEDG)

AEDG · 4 aa · @peptidemodel

bioassayed pep-00008 @peptidemodel refs: 13

all cards · 1 candidates against Anti-Aging

# id title author status refs ipSAE_d0chn
1 pep-00008 Epithalon: experimental longevity peptide (Epitalon / AEDG) pe@peptidemodel
13 0
1–1 of 1

target literature · 13 curated papers

[1]
Khavinson, V.K. et al. 2003 Bulletin of Experimental Biology and Medicine Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells
cited by
1
cards
[5]
Vishwanath, R. et al. 2025 Journal of Materials Chemistry B Programmable short peptides for modulating stem cell fate in tissue engineering and regenerative medicine
cited by
1
cards
[6]
Evans, C. et al. 1992 Science Cloning of a Delta Opioid Receptor by Functional Expression
cited by
1
cards
[7]
Tetè, G. et al. 2025 BMC Oral Health How short peptides interact with oral cells? A systematic review
cited by
1
cards
[8]
Kawakoshi, A. et al. 2004 Journal of Molecular Endocrinology Four natriuretic peptides (ANP, BNP, VNP and CNP) coexist in the sturgeon: identification of BNP in fish lineage
cited by
1
cards
[10]
Araj SK et al. 2025 International Journal of Molecular Sciences Overview of Epitalon—Highly Bioactive Pineal Tetrapeptide with Promising Properties
cited by
1
cards
recent news 2 articles

discussion · 0 threads

No discussion threads yet.